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RETINA VISION & LIMBS CAN BE SAVED
Omental Transplantation for limb salvage in Buergers,
Diabetes gangrene,
Restoring vision in Retinitis Pigmentosa, Macular degeneration, optic atrophy
(World wide accepted - Telecast in
Living Pulse II series by Discovery Channel)
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Eye can be revascularized by
Pedical Omentopexy, improve vision
(Retina pigmentosa, Macular degen, Choroditis, Central
artery occlusion Optic atrophy)
Myocardium total revascularization by T.M.R.
with Omentopexy
Dr. V.K. Agarwal, Rt. Director Medical Education, Dean and
Prof. Emeritus Medical College, Indore, India |
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Omentum a primitive structure, hanging as a fatty apron in abdomen6”x9” with vast network of blood vessels and lymphatic. It is known for its angiogenic properties. We used omentum for revascularization of the ischemic limbs and developed a technique (Agarwal technique) to lengthen a meter and brought it up to the toes in legs*(1) for last 25 yrs. with 85% good results and to retina in Eyes.**. We feel that this type of transplantation is effective because of its angiogenic properties and neovascularisation of ischeamic tissues. Vineburg 2 experiments have shown that omental grafts would develop communication with the local circulation which is ischemic in 4-8 days after omentopexy, by biological capillary and arteriolar anastomosis wherever the vessels are patent. Recent studies have shown this due to stem cells (CD+34 and Ly-1+B) which has power to migrate. This promote angiogenesis and repair and revascularize injured tissue.
So Omentopexy would be effective in cases with multiple blocks without distal runoff where direct reconstructive surgery is not possible.
We recommend the omentopexy as a choice of treatment to prevent amputation. We could save over 1000 patients from amputations with 85% good results in 16 years long term follow up. We have also used it with T.M.R. for Myocardial revascularisation with good results(3).
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In eye blindness due to avascular diseases of retina like Retinitis Pigmetosa, Age related Macular degeneration and optic atrophy, currently has no treatment(4,5), and patients constantly loose vision and become blind in spite of all available treatment.
Using our 25 yrs. experience of limb revascularisation with omentum and with published experimental study ,that intact omentum can be transplanted in eye safely, with evidence of developing bypass between omental and retinal vessels(6), we modified Agarwal technique(7) of Pedicle Omental transplantation to eye by which stomach vessel supplies eye (retinal bypass surgery).
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With our continue good results, Pedicle omental transfer offers new ray of hope in a-vascular diseases of retina Retinitis Pigmentosa to stop further detoration
and Improve vision. We recommend early operation as Post
operative recovery is directly proportionate to pre-op. vision. |
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